EPR核电厂循环水泵房(HPX)给循环冷却水(CRF)系统供水，为抗震Ⅰ类物项，厂址地基中非均质特性的影响尤为重要。以国内某核电厂实际厂址条件为背景，基于ANSYS分析平台建立了泵房-地基三维有限元整体计算模型，细致模拟捕虏体的力学特性和空间分布形态，并提出基于隐式Newmark的静动力时程分析法，对地基竖向变形及承载能力，基础底面接地率、抗滑和抗倾覆稳定性以及泵房主应力分布等进行了综合评价。计算结果表明，在该厂址实际的分布状态情况下，捕虏体的存在对泵房地基的安全性影响较小，局部压应力超标不影响整体稳定性，所评价指标均能满足规范要求，不需要进行地基处理措施，也验证了所建立静动力联合分析模型的可靠性及良好的工程适用性，结合ANSYS软件丰富的单元模型及非线性分析能力，该模型具有解决复杂核电结构非线性动力问题的潜力。

EPR nuclear power plant circulation water pump house(HPX) which is the seismic 1 item supplies water for circulating cooling water (CRF) system. So the influence of heterogeneity is particularly important in the site foundation. Based on the actual conditions of a domestic nuclear power plant site, a three dimensional finite element model of the pump house foundation is established by ANSYS platform. And the mechanical properties and spatial distribution pattern of xenoliths are simulated in detail. The static and dynamic time history analysis method is proposed based on Newmark method. This method can be used to comprehensively evaluate the vertical deformation of the foundation, bearing capacity, the base of the bottom surface rate, anti-sliding and anti-overturning stability, etc. The results of analysis show that, in the distribution of the site under practical, the existence of xenoliths has a little influence on the safety of pumping house foundation. Part compressive stress out of specification has no influence on overall stability. The foundation does not need to be processed because the index of the evaluation can meet the requirements of the specification. At the same time, the calculated results also verify reliability and good engineering applicability of the Static-Dynamic coupling analysis model. The model has the potential to solve the nonlinear dynamic problem of the complex nuclear power structure, with the combination of the ANSYS which has rich unit model and the capacity of nonlinear analysis.