The pipe-pile with holes can effectively accelerate the spatiotemporal dissipation of excess pore water pressure and reduce the negative effects of sinking-pile influence for the surrounding environment. However, the bearing capacity of pile will be weakened by the stress concentration phenomenon caused by opening hole. In order to explore the effect of the bearing capacity of pipe-pile due to opening holes, the static load tests of single pile have been carried out for the pipe-pile without hole and the pipe-pile with holes in soft soil foundation by using of the model tests, which are three kinds of opening holes. The settlement of the pile top and the pile strain in different positions caused by vertical load have been measured and analyzed. The Q-s settlement curves, axial force and side friction distributions of the all piles can be obtained. From the comparative analysis, it can be concluded that the decrease of axial force of pile of radial direction pipe-pile with holes is the minimum; the side friction of double direction pipe-pile with holes is the maximum.