Based on the theoretical analysis of displacement of tunnel and station induced by the foundation pit excavation, the disciplinarians of tunnel and station are summarized. The uneven deformation parameter is defined in the form of quantization, and the influence of the station on uneven deformation of tunnel and its prediction are researched. The results show that the subway station is uplifted, but the tunnel subsided during the pit excavation. The differential displacement between tunnel and station are great, and it is serious damaged to tunnel lining. The affected range of tunnel is 4 times as much as the depth of pit excavation. The range of uneven deformation region of tunnel is 1 times as much as the depth of pit excavation. The obtained formula of can predict the size and distribution of the uneven deformation of the tunnel caused by station. The results of this paper can provide useful reference for similar projects.