Abstract: With the development of cities in mountainous area, some buildings have to be situated on rock slope subgrade in order to save land. Interaction of slope subgrade and the building become a realistic research project. By using finite element method, interaction of a frame structure and raft foundation with homogeneous rock slope subgrade is computed. The computation examples are considered in 2m, 5m and 8m building distance circumstances. Rock slope subgrade is a 10 meters high vertical slope and foundation is raft. In interaction analysis, the interface of superstructure, raft foundation and slope subgrade satisfied the force balance and deformation compatibility requirements. In three building distances circumstances, strength and deformation development of the slope subgrade are researched. The internal force and deformation of raft foundation and superstructure are researched simultaneously. Some conclusions are drawn, so as to offer for reference in related engineering practice

Key words: building distance, homogeneous rock slope subgrade, frame structure, raft foundation, finite element analysis