Based on the dry-wet cycling experiment of concrete and micromechanics, the study of mechanical properties of concrete in seawater erosion is carried out. In the aspect of dry-wet cycling, by accelerated corrosion test method, the experiment of concrete specimens and mortar specimens which are made according to the ratio of concrete, has been completed after 0, 10, 20, 30, 40 and 50 times dry-wet cycles. Under the influence of seawater erosion on the concrete, its compressive strength is tested, together with the tensile strength of concrete, elastic modulus and stress-strain relationship, using the large static-dynamic triaxial test system for concrete. According to the theory of micromechanics, the concrete test block is numerically simulated on meso-level. Considering various components, the material nature of its components is assigned in accordance with the Weibull distribution. In order to reflect the influence of seawater erosion on the concrete, the strength and elastic ratio of mortar specimens are assigned according to the result of dry-wet cycling experiment. Finally, through the analysis and study of the concrete above all, the compressive strength reduction model, the tensile strength reduction model, and the elastic ratio reduction model, are determined with the change in the number of dry-wet circle.